— The Evidence

Studies Database

A structured, filterable database of peer-reviewed psilocybin studies design, sample size, findings, and limitations for each, with links to the primary sources and our plain-English breakdowns.

— The strongest evidence

Studies worth starting with

Psilocybin mushroom research specimen
2026established

Inside the Johns Hopkins Psilocybin Trials: Method, Findings, Limits

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Psilocybin for End-of-Life Anxiety: What the Research Shows — editorial image 1
2026established

Psilocybin for End-of-Life Anxiety: What the Research Shows

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Microdosing Psilocybin: What the Controlled Studies Show — editorial image 1
2026established

Microdosing Psilocybin: What the Controlled Studies Show

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The Griffiths2016TrialPsilocybinfortheFearattheEndofLife Quiet Psilocybin Therapy Room Hero.Png
2026established

The Griffiths 2016 Trial: Psilocybin for the Fear at the End of Life

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"A row of identical experiment setups repeated across a bench, suggesting replication, subtle mushroom motif."
2026established

Why One Study Is Never Enough: Replication in Psychedelic Science

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Psilocybin Against The Cigarette Smokerstruggle
2026established

The Johnson 2014 Study: Psilocybin Against the Cigarette

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Palhano Fontes 2019 Ayahuasca Depression Trial Herbalbrew
2026established

The Palhano-Fontes 2019 Trial: Ayahuasca Meets the Placebo Controlled Standard

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"A calm research desk with rating scales and charts, a subtle mushroom motif, methodical and clear."
2026established

How Scientists Measure Whether a Psychedelic Actually Works

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TheGukasyan2022Study Studycalendar
2026established

The Gukasyan 2022 Study: Does the Effect Actually Last?

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TheBogenschutz2022TrialPsilocybinandtheGripofAlcohol Empty Glass Alcohol Use Disorder Reflection.Png
2026established

The Bogenschutz 2022 Trial: Psilocybin and the Grip of Alcohol

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The Quiet Trial Reopeneddoor
2026established

The Grob 2011 Study: The Quiet Trial That Reopened a Closed Door

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"A calm long hallway of doors receding into the distance, suggesting the passage of time, subtle mushroom motif."
2026established

Following the Participants: What Long-Term Psychedelic Studies Try to Learn

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— Fresh from the journals

Most recent studies

"A calm abstract image of ordered patterns dissolving into freer ones, evoking brain entropy, subtle mushroom motif."
2026

REBUS and the Entropic Brain, Explained

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"A calm research desk with rating scales and charts, a subtle mushroom motif, methodical and clear."
2026established

How Scientists Measure Whether a Psychedelic Actually Works

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"A calm desk with an open research paper, a pen, and a cup of coffee, a subtle mushroom motif, inviting."
2026established

Reading a Real Study: A Layperson's Walkthrough

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"A row of identical experiment setups repeated across a bench, suggesting replication, subtle mushroom motif."
2026established

Why One Study Is Never Enough: Replication in Psychedelic Science

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"A calm long hallway of doors receding into the distance, suggesting the passage of time, subtle mushroom motif."
2026established

Following the Participants: What Long-Term Psychedelic Studies Try to Learn

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Psilocybin And The Locked Spiralstaircase
2026established

The Moreno 2006 Study: Psilocybin and the Locked Loop of OCD

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Evidence over headlines. Read the work itself.

Updated every Friday
Study Year Evidence Views
Psilocybin for Treatment-Resistant Depression: What the Research Actually Shows MMI Editorial 2026 established 778
Inside the Johns Hopkins Psilocybin Trials: Method, Findings, Limits MMI Editorial 2026 established 523
Psilocybin for End-of-Life Anxiety: What the Research Shows MMI Editorial 2026 established 405
Microdosing Psilocybin: What the Controlled Studies Show MMI Editorial 2026 established 354
The Griffiths 2016 Trial: Psilocybin for the Fear at the End of Life MMI Editorial 2026 established 344
Why One Study Is Never Enough: Replication in Psychedelic Science MMI Editorial 2026 established 323
The Johnson 2014 Study: Psilocybin Against the Cigarette MMI Editorial 2026 established 314
The Palhano-Fontes 2019 Trial: Ayahuasca Meets the Placebo Controlled Standard MMI Editorial 2026 established 307
How Scientists Measure Whether a Psychedelic Actually Works MMI Editorial 2026 established 284
The Gukasyan 2022 Study: Does the Effect Actually Last? MMI Editorial 2026 established 280
The Bogenschutz 2022 Trial: Psilocybin and the Grip of Alcohol MMI Editorial 2026 established 258
The Grob 2011 Study: The Quiet Trial That Reopened a Closed Door MMI Editorial 2026 established 255
Following the Participants: What Long-Term Psychedelic Studies Try to Learn MMI Editorial 2026 established 253
Reading a Real Study: A Layperson's Walkthrough MMI Editorial 2026 established 239
The Davis 2021 Trial: Psilocybin Steps Out of the Cancer Ward MMI Editorial 2026 established 222
The Moreno 2006 Study: Psilocybin and the Locked Loop of OCD MMI Editorial 2026 established 201
REBUS and the Entropic Brain, Explained MMI Editorial 2026 59

Each entry links to a plain-English breakdown and the primary source.

— How to read the evidence

What separates a strong study from a weak one

Sample size

A handful of participants tells you far less than a large, well-powered trial. Small pilots hint; big studies confirm.

Study design

Randomised, controlled, and blinded beats open-label every time. Design decides how much a finding can be trusted.

Confidence levels

Our ratings reflect the strength of the evidence, not the importance of the topic. Established outranks emerging.

Replication

One striking result is a starting point, not a conclusion. Findings earn weight when independent teams reproduce them.

Learn how to read a clinical trial
— From the archive

A visual field record

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-Magic-MushroomAlbino Forest caps-nature -Magic-MushroomMagic Mushroom InstituteAmanita Mushroom-Amanita Mushroom-Magic Mushroom InstituteEditorial Study 03Editorial Study 03Magic Mushroom InstituteConocybe 01Conocybe 01Magic Mushroom InstituteEditorial Study 04Editorial Study 04Magic Mushroom InstituteConocybe 02Conocybe 02Magic Mushroom InstituteEditorial Study 05Editorial Study 05Magic Mushroom InstituteConocybe 03Conocybe 03Magic Mushroom InstituteEditorial Study 06Editorial Study 06Magic Mushroom InstituteGymnopilus 04Gymnopilus 04Magic Mushroom InstituteEditorial Study 07Editorial Study 07Magic Mushroom InstituteGymnopilus 05Gymnopilus 05Magic Mushroom InstituteEditorial Study 08Editorial Study 08Magic Mushroom InstituteGymnopilus 06Gymnopilus 06Magic Mushroom InstituteEditorial Study 09Editorial Study 09Magic Mushroom InstituteGymnopilus 07Gymnopilus 07Magic Mushroom InstituteEditorial Study 10Editorial Study 10Magic Mushroom InstituteGymnopilus 08Gymnopilus 08Magic Mushroom 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— New evidence, every Friday

One study. One sentence. Why it matters.

Every Friday we add the most important new psilocybin study to this database and send you the 90-second breakdown. Stay current without reading the journals.

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